Efficacy and outcomes of CYP3A5 genotype-based tacrolimus dosing compared to conventional body weight-based dosing in living donor kidney transplant recipients

Conclusion: Genotype-based tacrolimus dosing leads to more subjects achieving the target tacrolimus C0 earlier. However, there may be a higher risk of tacrolimus nephrotoxicity.

Source: Indian Journal of Nephrology - June 6, 2022 Category: Urology & Nephrology Authors: T Yashwanth Raj M Edwin Fernando ND Srinivasa prasad S Sujit K Thirumal Valavan TS Harshavardhan Arvind Ramanathan Source Type: research