Oligoprogression in Metastatic, Castrate-Resistant Prostate Cancer —Prevalence and Current Clinical Practice

ConclusionsIn this study, nearly a third of patients on ARTT for CRPC were found to have OPD. OPD patients had a better PSA response on ART and a longer duration on ARTT before developing OPD as compared to those developing polyprogressive disease (Poly-PD). The majority of patients (70%) with OPD had lesions suitable for SBRT treatment. Prospective randomized control trials are needed to establish if there is a survival benefit of SBRT in oligoprogressive prostate cancer and to determine predictive indicators.
Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research