Non-small Cell Lung Cancer Surpassing the Elastic Layer Should Remain Classified as pT2a

We aimed to evaluate the prognostic value of visceral pleural invasion (VPI) on the survival of node-negative non-small cell lung cancer (NSCLC) ≤ 3 cm using a large cohort. The Kaplan–Meier method was used to compare overall survival (OS); competing risk analysis with Fine–Gray's test was used to compare cancer- specific survival (CSS) between groups. The least absolute shrinkage and selection operator (LASSO) penalized Cox regression model was used to identify prognostic factors. In total, 9,725 eligible cases were included in this study, and they were separated into three groups: tumor invasion beneath the elastic layer (PL0), 8,837 cases; tumor invasion surpassing the elastic layer (PL1), 505 cases; and tumor invasion to the visceral pleural surface (PL2), 383 cases.
Source: Seminars in Thoracic and Cardiovascular Surgery - Category: Cardiovascular & Thoracic Surgery Authors: Tags: THORACIC – Original Submission Source Type: research