Melatonin ameliorates tau-related pathology via the miR-504-3p and CDK5 axis in Alzheimer ’s disease

ConclusionsOur results suggest for the first time that melatonin alleviates tau-related pathologies through upregulation of miR-504-3p  expression by targeting the p39/CDK5 axis and provide novel insights into AD treatment strategies.
Source: Translational Neurodegeneration - Category: Neurology Source Type: research