Capmatinib suppresses LPS-induced interaction between HUVECs and THP-1 monocytes through suppression of inflammatory responses

CONCLUSION: These findings imply that CAP improves inflamed endothelial-monocyte adhesion via a PPAR/IL-10-dependent pathway. The current study provides in vitro evidence for a therapeutic approach for treating atherosclerosis.PMID:35483573 | DOI:10.1016/j.bj.2022.04.005

Source: Atherosclerosis - April 28, 2022 Category: Cardiology Authors: Hyung Sub Park A M Abd El-Aty Ji Hoon Jeong Taeseung Lee Tae Woo Jung Source Type: research