Unique Findings of Myocardial Improvement with Lower Left Ventricular Assist Device Pump Speed

Currently, optimizing hemodynamics and unloading in patients with left ventricular assist device (LVAD) relies on echocardiography and right heart catherization guidance for pump speed adjustments. However, the ideal unloading strategy to maximize reverse remodelling is uncertain - whether to provide maximal pump support to unload the heart ( ‘rest’), or maximize ventricular work with partial pump support (‘work’). Using non-invasively derived PV loops, we sought to characterize the longitudinal changes in chamber contractile parameters stroke work (SW), peak systolic pressure (LVPmax) and peak LV elastance (Ees) at different pum p speeds [2400 vs 2500 vs 2600 revolutions/min (rpm)].
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Tags: (434) Source Type: research