Coronary vessel formation in development and regeneration: origins and mechanisms

Neovascularization of the ischemic myocardium following infarction is vital for the survival of cardiomyocytes and prevention of heart failure. However, the intrinsic revascularization following ischemic injury in the heart is inadequate to restore blood flow to the infarcted myocardium. A comprehensive understanding of how coronary vasculature is constructed and what developmental pathways might be reactivated after infarction is beneficial to develop effective strategies for heart revascularization.
Source: Journal of Molecular and Cellular Cardiology - Category: Cytology Authors: Source Type: research