Liver-Directed Therapy for Metastatic Colon Cancer: Update

AbstractPurpose of ReviewTo discuss the emerging technologies in the field of Interventional radiology (IR) for the management of metastatic colorectal cancer (mCRC). We review the field of selective internal radiation therapy (SIRT), and well-known IR treatments, with a more focused investigation of radioembolization with Yttrium-90 (Y-90).Recent FindingsState-of-the-art treatment modalities for unresectable hepatic malignancies are crucial to increased patient survival. There are many options for the treating physician to manage and potentially cure patient ’s disease, with Y-90 as the cornerstone of liver neoplasm treatment. Additionally, current research in the fields of dosimetry and radiomics may allow for more optimized patient specific radiation doses.SummaryContinued advancements in colorectal surgery and interventional radiology have improved survival outcomes for patients with mCRC. Current treatment options are numerous and often include partial hepatectomy and SIRT. We review current literature and discuss our experiences in treating patients with advanced liver malignancies.
Source: Current Colorectal Cancer Reports - Category: Cancer & Oncology Source Type: research