Elevated Hemoglobin A1c Is Associated With Leaky Plaque Neovasculature as Detected by Dynamic Contrast-Enhanced Magnetic Resonance Imaging

CONCLUSIONS: Dynamic contrast-enhanced magnetic resonance imaging of carotid plaques suggested that plaque neovasculature in patients with diabetes is leaky, indicating enhanced capability of bringing blood constituents and facilitating extravasation of inflammatory cells, erythrocytes, and plasma proteins. Leaky plaque neovasculature correlated with hemoglobin A1c and may play a role in accelerated atherosclerosis progression in diabetes.PMID:35236109 | DOI:10.1161/ATVBAHA.121.317190

Source: Arteriosclerosis, Thrombosis and Vascular Biology - March 3, 2022 Category: Cardiology Authors: Beibei Sun Xiaoqian Ge Xiao Li Jianjian Zhang Zizhou Zhao Xiaosheng Liu Yan Zhou Jianrong Xu Huilin Zhao Jie Sun Source Type: research