Comment on Sj öholm et al. Association of Bariatric Surgery With Cancer Incidence in Patients With Obesity and Diabetes: Long-term Results From the Swedish Obese Subjects Study. Diabetes Care 2022;45:444–450

We were interested by the recent article inDiabetes Care by Sj öholm et al. (1), who reported that the incidence of cancer was reduced 21.3 years after bariatric surgery in patients with diabetes who participated in the Swedish Obese Subjects (SOS) cohort, with an especially promising 60% reduction for the 102 subjects whose diabetes remitted for 10 years, mainly (N = 91) after the intervention. In their discussion, the authors hypothesized that the most plausible mechanism to explain this remarkable result was the reduction of hyperinsulinism; however, the relation between initial serum insulin levels and later cancers was not significant.
Source: Diabetes Care - Category: Endocrinology Source Type: research