Genetic determinants of intracranial large artery stenosis in the northern Manhattan study

Intracranial stenosis is one of the most common causes of stroke worldwide. Several single nucleotide polymorphisms have been associated with intracranial atherosclerosis, which is inferred to be the most common underlying cause of intracranial large artery stenosis (ILAS). We previously reviewed known genetic variants related to ILAS in predominantly Asian cohorts, but their prevalence and role in ILAS among western multiethnic populations are uncertain.

Source: Journal of the Neurological Sciences - March 3, 2022 Category: Neurology Authors: Minghua Liu, Sanjeev Sariya, Farid Khasiyev, Giuseppe Tosto, Nicole D. Dueker, Ying Kuen Cheung, Clinton B. Wright, Ralph L. Sacco, Tatjana Rundek, Mitchell S.V. Elkind, Jose Gutierrez Source Type: research