Copolymer micelle-administered melatonin ameliorates hyperosmolarity-induced ocular surface damage through regulating PINK1 mediated mitophagy

CONCLUSIONS: Our findings demonstrated that Mel-Mic ameliorates hyperosmolarity induced ocular surface damage via PINK1 mediated mitophagy and may represent an effective treatment for DED possibly through acting MT1 receptor.PMID:35179400 | DOI:10.1080/02713683.2021.2022163

Source: Current Eye Research - February 18, 2022 Category: Opthalmology Authors: Jing Xu Peng Chen Guangfen Zhao Susu Wei Qiqi Li Chuanlong Guo Qilong Cao Xianggen Wu Guohu Di Source Type: research