Molecules, Vol. 27, Pages 1111: Unravelling the Helianthus tuberosus L. (Jerusalem Artichoke, Kiku-Imo) Tuber Proteome by Label-Free Quantitative Proteomics
Molecules, Vol. 27, Pages 1111: Unravelling the Helianthus tuberosus L. (Jerusalem Artichoke, Kiku-Imo) Tuber Proteome by Label-Free Quantitative Proteomics
Molecules doi: 10.3390/molecules27031111
Authors:
Ranjith Kumar Bakku
Ravi Gupta
Cheol-Woo Min
Sun-Tae Kim
Genboku Takahashi
Junko Shibato
Seiji Shioda
Fumiko Takenoya
Ganesh Kumar Agrawal
Randeep Rakwal
The present research investigates the tuber proteome of the ‘medicinal’ plant Jerusalem artichoke (abbreviated as JA) (Helianthus tuberosus L.) using a high-throughput proteomics technique. Although JA has been historically known to the Native Americans, it was introduced to Europe in the late 19th century and later spread to Japan (referred to as ‘kiku-imo’) as a folk remedy for diabetes. Genboku Takahashi research group has been working on the cultivation and utilization of kiku-imo tuber as a traditional/alternative medicine in daily life and researched on the lowering of blood sugar level, HbA1c, etc., in human subjects (unpublished data). Understanding the protein components of the tuber may shed light on its healing properties, especially related to diabetes. Using three commercially processed JA tuber products (dried powder and dried chips) we performed total protein extraction on the powdered samples using a label-free quantitate proteomic approach (mass spectrometry) and catalogued for the first time a comprehensive protein list for...
Source: Molecules - Category: Chemistry Authors: Ranjith Kumar Bakku Ravi Gupta Cheol-Woo Min Sun-Tae Kim Genboku Takahashi Junko Shibato Seiji Shioda Fumiko Takenoya Ganesh Kumar Agrawal Randeep Rakwal Tags: Article Source Type: research
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