A hyperpromiscuous antitoxin protein domain for the neutralization of diverse toxin domains [Microbiology]

Toxin–antitoxin (TA) gene pairs are ubiquitous in microbial chromosomal genomes and plasmids as well as temperate bacteriophages. They act as regulatory switches, with the toxin limiting the growth of bacteria and archaea by compromising diverse essential cellular targets and the antitoxin counteracting the toxic effect. To uncover previously uncharted TA...
Source: Proceedings of the National Academy of Sciences - Category: Science Authors: Tags: Microbiology Biological Sciences Source Type: research