MiR-155 Inhibits TP53INP1 Expression Leading to Enhanced Glycolysis of Psoriatic Mesenchymal Stem Cells

Psoriasis is a systemic disease with multiple associated comorbidities, including metabolic syndrome. Studies suggest that chronic inflammation is a central link between psoriasis and metabolic abnormalities. MiR-155 is a well-known microRNA that plays an important regulatory role in inflammation. Studies from our group and others have demonstrated an upregulation of miR-155 in psoriasis.

Source: Journal of Dermatological Science - February 3, 2022 Category: Dermatology Authors: Yanmin Liu, Xincheng Zhao, Juan Li, Ling Zhou, Wenjuan Chang, Jiajie Li, Ruixia Hou, Junqin Li, Guohua Yin, Xinhua Li, Kaiming Zhang Source Type: research