Revising the Role of Integrin Subunit β4 Expression in Colon Cancer Progression and Survival

ConclusionContradictory reports have suggested opposite roles for β4 expression in (colon) cancer progression. In the present large cohort of colon cancer patients, we found that β4 expression was not associated with worse clinical prognosis, but decreased with advanced pathological tumor stage. Future studies should establish whether loss of β4 expression prom otes invasive characteristics of colon cancer cells.

http://link.springer.com/10.1007/s12029-021-00787-8

Source: Journal of Gastrointestinal Cancer - February 3, 2022 Category: Cancer & Oncology Source Type: research