Impact of fibrinogen infusion on thrombin generation and fibrin clot structure in patients with inherited afibrinogenemia

CONCLUSIONS: In summary, fibrinogen infusion with a standard dose of FC increased but did not correct TG and led to formation of fibrin clots similar to those of patients with hypofibrinogenemia. All in all, our results do not support to biological evidence of hypercoagulability induced by FC in patients with afibrinogenemia.PMID:35045578 | DOI:10.1055/a-1745-0420

Source: Thrombosis and Haemostasis - January 19, 2022 Category: Hematology Authors: Claudia Djambas Khayat Rita Marchi St éphane Durual Thomas Lecompte Marguerite Neerman-Arbez Alessandro Casini Source Type: research