Essential Oils of Six Achillea Species: Chemical Profiles, Antimicrobial Potential and Toxicity toward Crustaceans

Chem Biodivers. 2022 Jan 13. doi: 10.1002/cbdv.202100905. Online ahead of print.ABSTRACTThis is the first comparative study on antimicrobial activity of essential oils (EOs) of six Achillea species ( A. crithmifolia , A. distans , A. grandifolia , A. millefolium , A. nobilis , and A. lingulata ) against ATCC and clinical microbial strains isolated from human swabs and on their toxicological potential on crustaceans. Oxygenated monoterpenes represented the major compound class in all six EOs, ranging from around 50% ( A. millefolium , A. nobilis , and A. lingulata ) up to over 80% ( A . crithmifolia and A. grandifolia ). Specific phytochemical profiles of the major volatiles were determined for each species. Still, borneol was the dominant compound in EOs of three yarrow species: A. distans , A. lingulata , and A. millefolium . Other major compounds were 1,8-cineole in A. crithmifolia, camphor in A. grandifolia , and artemisia ketone in A. nobilis EO. Antimicrobial activities of EOs were examined by a microdilution method revealing inhibitory action against all 15 studied strains in the range of 0.07-20.00 mg/mL (MICs). High toxicity (LC 50 <100 µg/mL) in Artemia salina acute toxicity bioassay was a shared characteristic, appearing in five out of six tested EOs, i.e. those isolated from A. lingulata , A. millefolium , A. distans , A. nobilis , and A. grandifolia . In both types of biological tests, A. lingulata EO has shown the highest and A . crithmifolia EO the lowest po...
Source: Chemistry and Biodiversity - Category: Biochemistry Authors: Source Type: research