Ninjinyoeito exerts an antidepressant ‐like effect by enhancing the central noradrenergic system

ConclusionNYT reduced immobility time in the tail suspension test, likely by increasing NE levels. The increased NE levels may activate the α1-adrenoceptor, thereby ameliorating the depression-like behavior. NYT may therefore improve depressive symptoms in patients by enhancing the noradrenergic system.

https://onlinelibrary.wiley.com/doi/10.1002/tkm2.1306?af=R

Source: Traditional and Kampo Medicine - January 15, 2022 Category: Complementary Medicine Authors: Soichiro Tsutsumi, Takuya Watanabe, Akinobu Hatae, Marika Hirata, Hiroya Omori, Chise Taniguchi, Masaki Nagao, Kaori Kubota, Shutaro Katsurabayashi, Katsunori Iwasaki Tags: ORIGINAL ARTICLE Source Type: research