Neuropsychiatric symptoms as predictor of poor clinical outcome in patients with vascular cognitive impairment#

Neuropsychiatric symptoms (NPS) are important and disruptive clinical features in patients with cognitive impairment and dementia.1,2 NPS are common across the clinical spectrum from mild cognitive impairment (MCI) to dementia, with 35-85% of patients with MCI and nearly all patients with dementia showing NPS.1 –3 NPS are associated with increased caregiver burden, higher costs of care, worse cognitive performance and poorer quality of life.4–7 NPS also predict a worse prognosis including more rapid progression of cognitive and functional decline, earlier institutionalization and death.

Source: The American Journal of Geriatric Psychiatry - January 1, 2022 Category: Geriatrics Authors: Yoni C.P. Sep, Anna E. Leeuwis, Lieza G. Exalto, Jooske M. Boomsma, Niels D. Prins, Jurre H. Verwer, Philip Scheltens, Wiesje M. van der Flier, Geert Jan Biessels, TRACE-VCI study group Source Type: research