RSSDI guidelines on thyroid dysfunction and diabetes

AbstractDiabetes and thyroid dysfunction coexist. There are several published guidances on screening detection and management of thyroid dysfunction in diabetes. The RSSDI has reviewed the evidence in the publish literature including India and provided a guidance to clinicians based on an expert review of the literature. Methods: A literature review was conducted of all published studies and the evidence was categorised by levels. The evidence was then reviewed by the expert group and a recommendation was provided with a grade. Summary: The relationship of hypothyroidism with T1DM is strong and warrants screening detection and treatment. While T2DM is frequently associated with thyroid dysfunction, the association is less strong. There appears to be a relationship between thyroid dysfunction and diabetes comorbidities. Drugs such as metformin may alter TSH levels. Thiazolidinediones may worsen dysthyroid orbitopathy. Gaps: The relationship between thyroid dysfunction and diabetes requires further study from a translational clinical and epidemiologic perspective leading to better evidence and recommendations.
Source: International Journal of Diabetes in Developing Countries - Category: Endocrinology Source Type: research