Paradoxical Reactions to Biologicals in Chronic Inflammatory Systemic Diseases

CONCLUSION: Paradoxical reactions induced by biological agents are a problem confronting physicians in multiple specialties. They need to be distinguished from infectious and neoplastic diseases and from autoimmune conditions of other types. The treatment options for paradoxical reactions include local treatment, symptomatic therapy, prednisolone administration, and the discontinuation or switching of the biological agent, although some patients will react with a further paradoxical reaction to a different biological agent that is used instead.PMID:34939919 | DOI:10.3238/arztebl.m2022.0067
Source: Deutsches Arzteblatt International - Category: General Medicine Authors: Source Type: research