LncRNA LINC00184 promotes docetaxel resistance and immune escape via miR-105-5p/PD-L1 axis in prostate cancer

CONCLUSIONS: LINC00184 promoted docetaxel resistance and immune escape in prostate cancer cells by adsorption of miR-105-5p, resulted in upregulation of the expression of PD-L1. LINC00184 could possibly be considered as a potential target for treatment in prostate cancer patients with docetaxel-resistance.PMID:34896914 | DOI:10.1016/j.imbio.2021.152163

Source: Immunobiology - December 13, 2021 Category: Allergy & Immunology Authors: Wei Zhang Jun Xin Jinjin Lai Wenbin Zhang Source Type: research