Pharmacokinetic Characterisation and Comparison of Bioavailability of Intranasal Fentanyl, Transmucosal, and Intravenous Administration through a Three-Way Crossover Study in 24 Healthy Volunteers

CONCLUSION: Pharmacokinetic parameters and bioavailability of the investigated intranasal fentanyl indicated suitability for its intended use as an intranasal PCA option.PMID:34880961 | PMC:PMC8648480 | DOI:10.1155/2021/2887773

Source: Pain Research and Management - December 9, 2021 Category: Anesthesiology Authors: S Nardi-Hiebl J W Ndieyira Y Al Enzi W Al Akkad T Koch G Geldner C Reyher L H J Eberhart Source Type: research