Treatment and Prevention of Brain Metastases in Small Cell Lung Cancer

Central nervous system (CNS) metastasis will develop in 50% of small cell lung cancer (SCLC) patients throughout disease course. Development of CNS metastasis poses a particular treatment dilemma due to the accompanied cognitive changes, poor permeability of the blood-brain barrier to systemic therapy and relatively advanced state of disease. Survival of patients with untreated SCLC brain metastases is generally
Source: American Journal of Clinical Oncology - Category: Cancer & Oncology Tags: Review Article Source Type: research