Bone morphogenetic protein 2 inhibits growth differentiation factor 8-induced cell signaling via upregulation of gremlin2 expression in human granulosa-lutein cells

CONCLUSIONS: Our findings provide new insight into the molecular mechanisms by which BMP2 modulates the cellular activity induced by GDF8 through the upregulated expression of their antagonist (GREM2).PMID:34838049 | DOI:10.1186/s12958-021-00854-6
Source: Reproductive Biology - Category: Reproduction Medicine Authors: Source Type: research