Late Breaking Abstract - Involvement of Orai1 Ca2+ channel in the pathogenesis of pulmonary arterial hypertension. Orai1 as a new potential therapeutic target ?

Conclusion: Altogether our results provide proof of concept that Orai1 should be considered as a new therapeutic target in PAH.

Source: European Respiratory Journal - November 25, 2021 Category: Respiratory Medicine Authors: Masson, B., Le Ribeuz, H., Sabourin, J., Woodhouse, E., Foster, R., Ruchon, Y., Dutheil, M., Boët, A., Ghigna, M.-R., Mercier, O., Beech, D., Benitah, J.-P., Bailey, M., Humbert, M., Montani, D., Capuano, V., Antigny, F. Tags: Pulmonary hypertension Source Type: research