Proton MRI assessment of lung structure and function in people with cystic fibrosis

Conclusion: This study demonstrates comprehensive lung MRI assessment in CF. UTE provides structural imaging without ionizing radiation. PREFUL MRI provides sensitive and regionally localized functional data, similar to 129Xe MRI, but is easier to perform. Together, these techniques could be used to assess response to therapeutics and potentially disease progression in pwCF in the future.Fig 1.UTE & PREFUL. Bronchiectatic (arrow) and cystic (arrowhead) changes are seen with UTE. Normal (green) and abnormal (purple) PREFUL ventilation is seen.

Source: European Respiratory Journal - November 25, 2021 Category: Respiratory Medicine Authors: Brooke, J., Safavi, S., Prayle, A. P., Ng, C., Paul, J., Bradley, C., Cooper, A., Munidasa, S., Zanette, B., Santyr, G. E., Barr, H., Major, G., Smyth, A., Gowland, P., Francis, S., Hall, I. P. Tags: Imaging Source Type: research