Changes of cardiovascular biomarkers and antioxidants during sedation by xylazine, detomidine, medetomidine, and dexmedetomidine in goats

In conclusion, IV administration of xylazine (100  μg kg−1), detomidine (50  μg kg−1), medetomidine (20  μg kg−1), and dexmedetomidine (5  μg kg−) showed cardiac side effects after 24  h in goats. These results suggest that usage of α2-adrenergic agonists in goats should be administered with caution, especially in goats with cardiovascular problems.
Source: Comparative Clinical Pathology - Category: Pathology Source Type: research