Hidradenitis Suppurativa and the Metabolic Syndrome A Comparative Cross-sectional Study of 3,207 Patients.

CONCLUSIONS: We found an association between HS and diabetes, hyperlipidemia, obesity, hypertension, and metabolic syndrome among a large community-based cohort of patients with HS. Clinicians should take into account that HS patients may have one or more undiagnosed components of the metabolic syndrome despite their young age. Thus, appropriate targeted screening is advised. This article is protected by copyright. All rights reserved. PMID: 25760289 [PubMed - as supplied by publisher]
Source: The British Journal of Dermatology - Category: Dermatology Authors: Tags: Br J Dermatol Source Type: research

Related Links:

Authors: Campos-Borges HC, Sanz-González SM, Zanón-Moreno V, Millán Salvador JM, Pinazo-Duran MD PMID: 31629562 [PubMed - as supplied by publisher]
Source: Archivos de la Sociedad Espanola de Oftalmologia - Category: Opthalmology Tags: Arch Soc Esp Oftalmol Source Type: research
In this study, we assessed effects of LPZ on adipocyte differentiation and function by using 3T3-L1 preadipocytes and HFD-induced obesity mice as an in vitro and in vivo model, respectively.Main methodsOil red O staining and intracellular triacylglycerol content were used to determine lipid accumulation. Glucose uptake was performed to measure mature adipocyte function. Expression of adipocyte genes was determined by qRT-PCR and immunoblotting.Key findingsLPZ has dual effects on differentiation of 3T3-L1 cells. At low concentrations, LPZ enhanced adipocyte differentiation via induction of PPARγ and C/EBPα, two ...
Source: Life Sciences - Category: Biology Source Type: research
Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy - Category: Endocrinology Tags: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy Source Type: research
Publication date: Available online 20 October 2019Source: Microvascular ResearchAuthor(s): Wayne Smith, Konstantin E. Kotliar, Leandi Lammertyn, Nthai E. Ramoshaba, Walthard Vilser, Hugo W. Huisman, Aletta E. SchutteAbstractPurposeGlobally, a detrimental shift in cardiovascular disease risk factors and a higher mortality level are reported in some black populations. The retinal microvasculature provides early insight into the pathogenesis of systemic vascular diseases, but it is unclear whether retinal vessel calibers and acute retinal vessel functional responses differ between young healthy black and white adults.MethodsW...
Source: Microvascular Research - Category: Biochemistry Source Type: research
CONCLUSIONS: HS is associated with a variety of comorbid conditions that should be considered to perform targeted routine screening and to improve HS management. PMID: 30295448 [PubMed - as supplied by publisher]
Source: Giornale Italiano di Dermatologia e Venereologia - Category: Dermatology Tags: G Ital Dermatol Venereol Source Type: research
The metabolic syndrome —otherwise called syndrome X, insulin resistance syndrome, Reaven syndrome, and “the deadly quartet”—is the name given to the aggregate of clinical conditions comprising central and abdominal obesity, systemic hypertension, insulin resistance (or type 2 diabetes mellitus), and atherogenic dy slipidemia. It is a prothrombotic and proinflammatory state characterized by increased inflammatory cytokine activity. In addition to inflammatory dermatoses such as psoriasis, lichen planus, and hidradenitis suppurativa, metabolic syndrome is also commonly associated with accelerated athe...
Source: Clinics in Dermatology - Category: Dermatology Authors: Source Type: research
ConclusionThe application of these recommendations will facilitate the dermatologist practice, and benefit HS patients’ health and quality of life.This article is protected by copyright. All rights reserved.
Source: Journal of the European Academy of Dermatology and Venereology - Category: Dermatology Authors: Tags: Original Article Source Type: research
CONCLUSION: Emerging scientific evidence points to close associations between MetS and common dermatological diseases necessitating to integrate this perspective into clinical management of these diseases. The dermatologist is a key player in early detection of MetS. PMID: 27815622 [PubMed - as supplied by publisher]
Source: Der Hautarzt: Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete - Category: Dermatology Tags: Hautarzt Source Type: research
Hidradenitis suppurativa (HS) is a chronic inflammatory dermatological disease characterized by nodules, sinus tracts, and subsequent scarring in inverse areas with a prevalence reported from 1-4% [1,2]. HS has been associated with metabolic syndrome, which is a cluster of arterial cardiovascular risk factors i.e. obesity, hypertension, diabetes, and dyslipidemia [3]. Several of these risk factors as well as raised levels of the inflammatory marker C-reactive protein, are also linked to venous thromboembolism i.e.
Source: Journal of Dermatological Science - Category: Dermatology Authors: Tags: Letter to the Editor Source Type: research
ConclusionsWe found an association between HS and diabetes, hyperlipidaemia, obesity, hypertension and metabolic syndrome among a large community‐based cohort of patients with HS. Clinicians should take into account that patients with HS may have one or more undiagnosed components of metabolic syndrome despite their young age. Thus, appropriate targeted screening is advised.
Source: British Journal of Dermatology - Category: Dermatology Authors: Tags: Epidemiology and Health Services Research Source Type: research
More News: Databases & Libraries | Dermatology | Diabetes | Eating Disorders & Weight Management | Endocrinology | Health | Health Management | Hidradenitis | Hypertension | International Medicine & Public Health | Metabolic Syndrome | Middle East Health | Obesity | Primary Care | Skin | Smokers | Study