Comparison of in vitro activities of plazomicin and other aminoglycosides against clinical isolates of Klebsiella pneumoniae and Escherichia coli

ConclusionsAlthough plazomicin showed excellentin vitro activity against carbapenem-susceptible isolates, the plazomicin resistance rate increased to 35.6% among carbapenem-resistantK. pneumoniae and further increased to 45.5% amongblaNDM-positive isolates.
Source: Journal of Antimicrobial Chemotherapy - Category: Microbiology Source Type: research