Serum fibroblast growth factor 21 levels is associated with lower extremity atherosclerotic disease in Chinese female diabetic patients

Background:
Fibroblast growth factor 21 (FGF21) is an emerging metabolic regulator associated with glucose and lipid metabolism, and it is still unclear whether FGF21 is related to atherosclerosis. Here, we explored the potential link between FGF21 and lower extremity atherosclerotic disease (LEAD) in type 2 diabetic patients.
Methods:
A cross-sectional study was conducted on 504 type 2 diabetic patients (283 men, 221 women). LEAD was defined by Ankle-brachial index (ABI)

Source: Cardiovascular Diabetology - March 11, 2015 Category: Cardiology Authors: Xiaoyan ZhangYanyun HuHui ZengLianxi LiJungong ZhaoJun ZhaoFang LiuYuqian BaoWeiping Jia Source Type: research