Characterization of mitochondrial DNA quantity and quality in the human aged and Alzheimer ’s disease brain

Mitochondrial dysfunction is a feature of neurodegenerative diseases, including Alzheimer ’s disease (AD). Changes in the mitochondrial DNA copy number (mtDNAcn) and increased mitochondrial DNA mutation burden ...

Source: Molecular Neurodegeneration - November 6, 2021 Category: Neurology Authors: Hans-Ulrich Klein, Caroline Trumpff, Hyun-Sik Yang, Annie J. Lee, Martin Picard, David A. Bennett and Philip L. De Jager Tags: Research article Source Type: research