Harlequin syndrome, apnea, and acute on chronic hemiparesis: an atypical pediatric case of Chiari I with holocord syringohydromyelia

A four-year-old, right handed, full term female, with mild global developmental delay, presented to the emergency department for evaluation of progressive right hemiparesis. Her development was significant for walking at 18 months and expressive speech delay. At 3.5 years old, she was diagnosed with Harlequin syndrome (Figure 1) after multiple episodes of left hemifacial flushing with physical exertion. Concurrently, she began dragging her right leg, and was diagnosed with hemiplegic cerebral palsy by an outside hospital.

Source: Pediatric Neurology - October 25, 2021 Category: Neurology Authors: Stephen Chrzanowski, Alexandra Baker, Leslie Hayes, Hanalise V. Huff, Lauren Fanty, Mark Proctor, Edward Yang, Kelsey Miller, Kiran Maski Tags: Short Communication Source Type: research