A Retrospective Analysis of R-MPV Plus Response-adapted Whole-brain Radiotherapy for Elderly Patients with Primary Central Nervous System Lymphoma

Conclusion This regimen in elderly patients is unsatisfactory because of delayed neurotoxicity. We should consider maintaining an adequate MTX intensity, postponing or minimizing WBRT, and choosing high-dose consolidation therapy for select patients.PMID:34670884 | DOI:10.2169/internalmedicine.7805-21

Source: Internal Medicine - October 21, 2021 Category: Internal Medicine Authors: Yutaro Suzuki Naoto Imoto Shunichi Ishihara Shinji Fujiwara Rie Ito Toshiyasu Sakai Satomi Yamamoto Isamu Sugiura Shingo Kurahashi Source Type: research