Efficacy Study of Acupuncture to Treat CP/CPPS by fMRI

Condition:   Chronic Prostatitis With Chronic Pelvic Pain Syndrome Interventions:   Device: Acupuncture;   Device: Sham acupuncture;   Other: fMRI scan Sponsors:   Shanghai University of Traditional Chinese Medicine;   Huashan Hospital Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials

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Research suggests that a good patient-clinician therapeutic alliance can improve clinical outcomes. In this ongoing, longitudinal study, we applied fMRI hyper-scanning to determine whether behavioral, neural, and clinical variables associated with the therapeutic relationship between chronic pain patients and their clinicians influences clinical outcomes. Ten women with fibromyalgia (mean age=40, SD=10.71, each group N=5) were randomly assigned to either an Augmented (warm/attentive) or Limited (neutral/business-like) interaction style, and were treated with electro-acupuncture for 6 biweekly sessions.
Source: The Journal of Pain - Category: Materials Science Authors: Source Type: research
Abstract Chronic shoulder pain (CSP) is the third most common musculoskeletal problem. For maximum treatment effectiveness, most acupuncturists usually choose acupoint in the nonpainful side, to alleviate pain or improve shoulder function. This method is named opposite needling, which means acupuncture points on the right side are selected for diseases on the left side and vice versa. However, the underlying neural mechanisms related to treatment are currently unclear. The purpose of this study was to determine whether different mechanisms were observed with contralateral and ipsilateral acupuncture at Tiaokou (ST...
Source: Neural Plasticity - Category: Neurology Authors: Tags: Neural Plast Source Type: research
In this study, we used machine learning approaches to test if pre-treatment rsFC can predict responses to both real and sham acupuncture treatments in cLBP patients. Fifty cLBP patients participated in 4 weeks of either real (N = 24, age = 39.0 ± 12.6, 16 females) or sham acupuncture (N = 26, age = 40.0 ± 13.7, 15 females) treatment in a single-blinded trial, and a resting-state fMRI scan prior to treatment was used in data analysis. Both real and sham acupuncture can produce significant pain reduction, with those receiving real treatment experiencing greater pain relief than those r...
Source: NeuroImage: Clinical - Category: Radiology Source Type: research
We examined the expression of TRPV1 in peripheral tissue and DRG neurons of CPIP model rats and we studied whether CPIP model could induce peripheral sensitization of TRPV1 channel and enhance DRG neuron excitability. Then we examined the therapeutic effects of locally applied TRPV1 specific antagonist AMG9810 on pain responses of CPIP model rats. Lastly, we explored the effects of AMG9810 on DRG neuron hyperexcitability and spinal glial activation induced by CPIP. Our results demonstrate that TRPV1 plays an important role in mediating the behavioral hypersensitivity of CPIP model rats via promoting peripheral nociceptor a...
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
Conclusions With comprehensive treatments, 27.9% of patients had successful opioid tapering with opioid abstinence for over a year. The use of mirtazepine, topiramate, or likely bupropion was associated with successful opioid tapering in the medication assisted treatment with temporary use of methadone. Opioid tapering may be a practical option and should be considered for managing prescription OUD. Implications For patients with OUD, indefinite opioid maintenance treatment may not be necessary. Considering the ethical values of autonomy, nonmaleficence, and beneficence, clinicians should provide patients with OUD the opti...
Source: Scandinavian Journal of Pain - Category: Anesthesiology Source Type: research
We present a case of 66-year-old female patient who has been treated by both conventional and Chinese traditional medicine after diagnosis was confirmed in 2008 as MS and antiphospholipid syndrome associated with CNS vasculitis. After diagnosis with clinical image confirmed with CT and MRI scan, where demyelinating zones were present, she started pharmacological therapy without major improvement. Patient suffered with fatigue, walking difficulties, weakness, was unable to articulate due to vocal cords spasms. We started acupuncture treatment in 2010 with herbal supplement therapy as well and patient had in total of 19...
Source: Neuroendocrinology Letters - Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research
(Follow me at @DrEvaSelhub) In the 1890s, a Shakespearean actor named Frederick Matthias Alexander set out to discover why he often lost his voice when he performed. (Imagine yourself as a Shakespearean actor, completely dependent on your voice to pay your bills, finding yourself without a voice just when you needed to perform!) Needless to say, Alexander had to figure out why this was happening. He began by observing himself in multiple mirrors while he prepared to perform. Indeed, he did discover that something changed prior to his speaking: He was contracting the muscles in his upper body, especially his neck, so strong...
Source: New Harvard Health Information - Category: Consumer Health News Authors: Tags: Back Pain Behavioral Health Complementary and alternative medicine Pain Management alexander technique Source Type: news
I first met Mr. J when I was a newly minted doctor at Boston Medical Center (BMC). He walked into my office with an air of confidence, his head high, but his eyes rested warily upon me. He had been a member of the Black Panthers and now was a strong member in the organized labor movement. His gaze quickly softened and crumbled though as I sat with him and asked him gently what brought him in. He was in a broken place — his body ravaged by years of pain that now interfered with his everyday activities: his blood pressure was high and contributing to daily headaches, his once strong body had grown corpulent with inacti...
Source: Health Affairs Blog - Category: Health Management Authors: Tags: Equity and Disparities Health Professionals Hospitals Innovations in Care Delivery Organization and Delivery Public Health Boston Medical Center ICD-10 code IMGV Institute of Medicine International Classification of Diseases National Source Type: blogs
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