Surgical de-escalation in gynecologic oncology

Bull Cancer. 2021 Oct 7:S0007-4551(21)00358-1. doi: 10.1016/j.bulcan.2021.06.012. Online ahead of print.ABSTRACTThe evolution of knowledge in gynecologic oncology is leading to surgical de-escalation in several areas, particularly in lymph node staging. Sentinel lymph node biopsy that was initially used in low and intermediate risk endometrial cancer, has now been extended to high-intermediate and high-risk endometrial cancer. Sentinel lymph node biopsy plays also an important role in the nodal staging of early-stage cervical cancer. The radicality of hysterectomies in patients with early cervical cancer is under debate. Similarly, surgical staging with para-aortic lymphadenectomy in locally advanced cervical cancer should be performed only for few cases. Systematic pelvic and para-aortic lymphadenectomy in patients with advanced ovarian cancers is not recommended anymore.PMID:34629168 | DOI:10.1016/j.bulcan.2021.06.012

Source: Bulletin du Cancer - October 11, 2021 Category: Cancer & Oncology Authors: Fran çois Zaccarini Claire Sanson Amandine Maulard St éphanie Scherier Patricia Pautier Alexandra Leary Catherine Genestie Cyrus Chargari Philippe Morice S ébastien Gouy Source Type: research