RAGE mediates the pro-migratory response of extracellular S100A4 in human thyroid cancer cells.
Conclusion: Our data have identified the RAGE/ -DIA-1 signaling system as a mediator for the pro-migratory response of extracellular S100A4 in human thyroid cancer. Thus, therapeutic targeting of the RAGE/DIA-1/small GTPases signaling may successfully reduce local invasion and metastasis in thyroid cancer.
PMID: 25744544 [PubMed - as supplied by publisher]
Source: Thyroid : official journal of the American Thyroid Association - Category: Endocrinology Tags: Thyroid Source Type: research
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