Ethanol and opioids do not act synergistically to depress excitation in carotid body type I cells

Conclusion

These results indicate for the first time that while opioids may suppress breathing via an action at the level of the carotid bodies, ethanol is unlikely to potentiate inhibition via this pathway. Thus, the synergistic effects of ethanol and opioids on ventilatory parameters are likely mediated by central rather than peripheral actions.

Source: NeuroReport - October 7, 2021 Category: Neurology Tags: Cellular, Molecular and Developmental Neuroscience Source Type: research