Relationships Between Indices of Tumor Aggressiveness in Hepatocellular Carcinoma

ConclusionsMultifocality and PVT appear to be separate processes, each increasing with increase in MTD and AFP levels. The data support the hypothesis that in hepatocarcinogenesis, various factors cause increase in MTD, that in turn causes increased multifocality and PVT, which are non-co-dependent. However, both multifocality and PVT mechanisms involve both HCC cell growth and invasiveness, multifocality in liver parenchyma, and PVT in the portal vein.
Source: Journal of Gastrointestinal Cancer - Category: Cancer & Oncology Source Type: research