Cancers, Vol. 13, Pages 4860: Artificial Light at Night Reduces Anxiety-Like Behavior in Female Mice with Exacerbated Mammary Tumor Growth

Cancers, Vol. 13, Pages 4860: Artificial Light at Night Reduces Anxiety-Like Behavior in Female Mice with Exacerbated Mammary Tumor Growth Cancers doi: 10.3390/cancers13194860 Authors: William H. Walker Raegan M. Kvadas Laura E. May Jennifer A. Liu Jacob R. Bumgarner James C. Walton A. Courtney DeVries Robert T. Dauchy David E. Blask Randy J. Nelson Artificial light at night (ALAN) is a pervasive phenomenon. Although initially assumed to be innocuous, recent research has demonstrated its deleterious effects on physiology and behavior. Exposure to ALAN is associated with disruptions to sleep/wake cycles, development of mood disorders, metabolic disorders, and cancer. However, the influence of ALAN on affective behavior in tumor-bearing mice has not been investigated. We hypothesize that exposure to ALAN accelerates mammary tumor growth and predict that ALAN exacerbates negative affective behaviors in tumor-bearing mice. Adult (> 8 weeks) female C3H mice received a unilateral orthotropic injection of FM3A mouse mammary carcinoma cells (1.0 × 105 in 100 μL) into the fourth inguinal mammary gland. Nineteen days after tumor inoculation, mice were tested for sucrose preference (anhedonia-like behavior). The following day, mice were subjected to an open field test (anxiety-like behavior), followed by forced swim testing (depressive-like behavior). Regardless of tumor status, mice housed in ALAN increased body mass through the first ten days....
Source: Cancers - Category: Cancer & Oncology Authors: Tags: Article Source Type: research

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Source: Iranian Journal of Pharmaceutical Research - Category: Drugs & Pharmacology Source Type: research
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Source: PsyBlog | Psychology Blog - Category: Psychiatry & Psychology Authors: Tags: Depression subscribers-only Source Type: blogs
Are dreams a message from the soul or meaningless ‘brain farts’? Groups dedicated to interpretation are thrivingJason DeBord regrets the demise of an old parlour game once much-loved in the 19th century: What Did I Eat Last Night? It involved a player recounting their dreams – recorded in a journal upon waking – as an audience was challenged to guess what dream-provoking food they had consumed for the previous night’s supper, be it stilton, rarebit or undercooked or cured meats (all understood to be culprits when it came to colourful dreaming).“Maybe you had eaten rare beef and then you ...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Sleep Psychology Health & wellbeing Life and style Science Source Type: news
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Source: Current Opinion in Rheumatology - Category: Rheumatology Tags: OSTEOARTHRITIS: Edited by Mukundan Attur Source Type: research
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Source: Dimensions of Critical Care Nursing - Category: Nursing Tags: Research DIMENSION Source Type: research
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Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
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