Bradykinin Protects Human Endothelial Progenitor Cells from High-Glucose-Induced Senescence through B2 Receptor-Mediated Activation of the Akt/eNOS Signalling Pathway

CONCLUSION: BK, acting through PI3K-AKT-eNOS signalling pathways, reduced hTERT translocation, increased the relative length of telomeres while reducing mtDNA copy number, and finally protected against EPC senescence induced by HG.PMID:34557552 | PMC:PMC8452971 | DOI:10.1155/2021/6626627

Source: Cell Research - September 24, 2021 Category: Cytology Authors: Yuehuan Wu Cong Fu Bing Li Chang Liu Zhi He Xing-Er Li Ailing Wang Genshan Ma Yuyu Yao Source Type: research