Guidelines for Pediatric Unrelated Cord Blood Transplantation —Unique Considerations

Cord blood (CB) is the stem cell source of choice for approximately 30% of pediatric patients undergoing hematopoietic cell transplantation. Cord blood is readily available and is a particularly appealing stem cell source for patients who lack appropriate HLA matched related or unrelated donors. Pediatric cord blood transplant (CBT) recipients have low rates of disease relapse in the malignant setting and very low rates of chronic GVHD. In addition, CB has unique properties that make it the stem cell source of choice for some non-malignant conditions such as metabolic disorders.

Source: Biology of Blood and Marrow Transplantation - September 24, 2021 Category: Hematology Authors: Ann Dahlberg, Joanne Kurtzberg, Jaap Boelens, Caridad Martinez, Paul Carpenter, American Society for Transplantation and Cellular Therapy Cord Blood Special Interest Group Source Type: research