New Perspective on the Geographic Distribution and Evolution of Lymphocytic Choriomeningitis Virus, Central Europe

We report LCMV prevalence in natural mouse populations from a Czech Republic-Germany transect and genomic characterization of 2 new LCMV variants from the Czech Republic. We demonstrate that the main division in the LCMV phylogenetic tree corresponds to mouse host subspecies and, when the virus is found in human hosts, the mouse subspecies found at the spillover location. Therefore, LCMV strains infecting humans can be predicted by the genetic structure of house mice.PMID:34545789 | DOI:10.3201/eid2710.210224

Source: Emerging Infectious Diseases - September 21, 2021 Category: Infectious Diseases Authors: Alena Forn ůsková Zuzana Hiadlovsk á Milo š Macholán Jaroslav Pi álek Jo ëlle Goüy de Bellocq Source Type: research