Autoimmune & inflammatory nmd

A 72-year-old woman presented with a 6-month history of anorexia, weight loss (-14kg) and myalgia in upper limbs. Clinical examination showed moderate proximal muscle weakness in upper limbs and crepitation at lung auscultation, but no skin rash nor joint involvement. Biological assessment disclosed increased C-reactive protein (68 µM) and creatine-kinase (3800 U/l) serum levels and anti-nuclear and -PL7 autoantibodies at immunological screening. Thoracic CT-scan showed abnormalities consistent with interstitial pneumonia.
Source: Neuromuscular Disorders - Category: Neurology Authors: Source Type: research