Imaging
Quantitative MRI (qMRI) of skeletal muscles is a promising method to objectively assess muscle involvement in Duchenne muscular dystrophy (DMD) and a potential outcome measure in clinical trials. qMRI data of the upper extremity (UE) muscles in non-ambulant DMD patients are limited. Therefore, we longitudinally assessed qMRI and UE functional outcome measures in this stage of the disease. 4-point Dixon MRI scans (3T) of the right upper arm, performance of the upper limb (PUL) version 2.0 and elbow flexion and grip strength were measured at baseline, 12 and 18 months follow-up.
Source: Neuromuscular Disorders - Category: Neurology Authors: A. Prins, K. Naarding, M. Holst van der, J. Verschuuren, E. Niks, H. Kan Source Type: research
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