Very Popular Food Linked To Brain Shrinkage

The shrinkage is linked to developing Alzheimer's disease or another type of dementia.
Source: PsyBlog | Psychology Blog - Category: Psychiatry & Psychology Authors: Tags: Dementia Source Type: blogs

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This cross-sectional cohort study evaluates plasma glial fibrillary acidic protein levels throughout the entire Alzheimer disease continuum, from preclinical Alzheimer disease to Alzheimer disease dementia, compared with cerebrospinal fluid glial fibrillary acidic protein.
Source: JAMA Neurology - Category: Neurology Source Type: research
Conclusions: APOE gene rs429358 and BIN1 gene 7561528 genes may affect the susceptibility to DAT in a Chinese Han population.
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
In this study, we therefore analysed the influence of lithium treatment on lifespan and parameters of health during ageing in mice. To determine the concentration of lithium suitable to be administered in a longitudinal ageing study, we first tested the effects of lithium chloride (LiCl) in doses from 0.01 to 2.79 g LiCl per kg chow. C57Bl/6J mice fed with 1.05-2.79 g/kg LiCL in the diet showed lithium plasma levels between 0.4 and 0.8 mM/l. While plasma levels to 0.4 and 0.8 mM/l are well tolerated by human patients, at doses above 1.44 g LiCl/kg, we observed an obvious dose-dependent polydipsia combined with a dis...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Neurobiol Aging. 2021 Sep 15;109:43-51. doi: 10.1016/j.neurobiolaging.2021.09.010. Online ahead of print.ABSTRACTBrain atrophy occurs in aging even in the absence of dementia, but it is unclear to what extent this is due to undetected preclinical Alzheimer disease. Here we examine a cross-sectional cohort (ages 18-88) free from confounding influence of preclinical Alzheimer disease, as determined by amyloid PET scans and three years of clinical evaluation post-imaging. We determine the regional strength of age-related atrophy using linear modeling of brain volumes and cortical thicknesses with age. Age-related atrophy was ...
Source: Neurobiology of Aging - Category: Geriatrics Authors: Source Type: research
Arch Clin Neuropsychol. 2021 Oct 13;36(7):1257-1265. doi: 10.1093/arclin/acab052.ABSTRACTAlzheimer' dementia is a large and growing public health problem. Of utmost importance for limiting the impact of the disease on society is the prevention of dementia, that is, delay onset either by years whereby death ensues prior to dementia onset. The Religious Orders Study and the Rush Memory and Aging Project are two harmonized cohort studies of aging and dementia that include organ donation at death. Ongoing since 1994 and 1997, respectively, we published on the association of numerous experiential, psychological, and medical ris...
Source: Archives of Clinical Neuropsychology - Category: Psychiatry & Psychology Authors: Source Type: research
Alzheimer Dis Assoc Disord. 2021 Oct 15. doi: 10.1097/WAD.0000000000000472. Online ahead of print.ABSTRACTBACKGROUND: Rapidly progressive dementia (RPD) is a clinical syndrome developing in
Source: Alzheimer Disease and Associated Disorders - Category: Psychiatry Authors: Source Type: research
CONCLUSION: Conventional visual reading of FDG-PET is moderately accurate in distinguishing between MCI-LB and MCI-AD, and is not significantly improved by univariate single-subject VBA but by a VROI analysis built on macro-regions, allowing for high accuracy independent of reader skills.PMID:34651219 | DOI:10.1007/s00259-021-05568-w
Source: Molecular Medicine - Category: Molecular Biology Authors: Source Type: research
Arch Clin Neuropsychol. 2021 Oct 13;36(7):1257-1265. doi: 10.1093/arclin/acab052.ABSTRACTAlzheimer' dementia is a large and growing public health problem. Of utmost importance for limiting the impact of the disease on society is the prevention of dementia, that is, delay onset either by years whereby death ensues prior to dementia onset. The Religious Orders Study and the Rush Memory and Aging Project are two harmonized cohort studies of aging and dementia that include organ donation at death. Ongoing since 1994 and 1997, respectively, we published on the association of numerous experiential, psychological, and medical ris...
Source: Archives of Clinical Neuropsychology - Category: Psychiatry & Psychology Authors: Source Type: research
CONCLUSION: Conventional visual reading of FDG-PET is moderately accurate in distinguishing between MCI-LB and MCI-AD, and is not significantly improved by univariate single-subject VBA but by a VROI analysis built on macro-regions, allowing for high accuracy independent of reader skills.PMID:34651219 | DOI:10.1007/s00259-021-05568-w
Source: Molecular Medicine - Category: Molecular Biology Authors: Source Type: research
Alzheimer Dis Assoc Disord. 2021 Oct 15. doi: 10.1097/WAD.0000000000000472. Online ahead of print.ABSTRACTBACKGROUND: Rapidly progressive dementia (RPD) is a clinical syndrome developing in
Source: Alzheimer Disease and Associated Disorders - Category: Psychiatry Authors: Source Type: research
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