Early platelet dysfunction in patients receiving extracorporeal membrane oxygenation is associated with mortality

In conclusion, platelets from ECMO patients are severely dysfunctional predisposing patients to bleeding complications and poor outcome. Platelet dysfunction on day 1 of ECMO detected by the platelet surface markers CD63 and activated GPIIb/IIIa is associated with mortality. CD63 and activated GPIIb/IIIa may therefore serve as novel prognostic biomarkers, but future studies are required to determine their true potential.
Source: Journal of Thrombosis and Thrombolysis - Category: Hematology Source Type: research