Atypical antipsychotic drugs deregulate the cholesterol metabolism of macrophage-foam cells by activating NOX-ROS-PPAR γ-CD36 signaling pathway

Clinical reports indicate that schizophrenia patients taking atypical antipsychotic drugs suffer from metabolism diseases including atherosclerosis. However, the mechanisms underlying the detrimental effect of atypical antipsychotic drugs on atherosclerosis remain to be explored.

Source: Metabolism - Clinical and Experimental - August 5, 2021 Category: Biomedical Science Authors: Chia-Hui Chen, Shr-Jeng Jim Leu, Chiao-Po Hsu, Ching-Chian Pan, Song-Kun Shyue, Tzong-Shyuan Lee Tags: Basic Science Source Type: research