Pre-Operative Plasma Extracellular Vesicle Proteins are Associated with a High Risk of Long Term Secondary Major Cardiovascular Events in Patients Undergoing Carotid Endarterectomy

CONCLUSION: EV derived pre-operative plasma levels of cystatin C, serpin C1, CD14, and serpin F2 were independently associated with an increased long term risk of MACE after CEA and are thus markers for residual cardiovascular risk. EV derived CD14 levels could improve the identification of high risk patients who may benefit from secondary preventive add on therapy in order to reduce future risk of MACE.PMID:34511318 | DOI:10.1016/j.ejvs.2021.06.039

Source: PubMed: Eur J Vasc Endovasc ... - September 13, 2021 Category: Surgery Authors: Nathalie Timmerman Farahnaz Waissi Mirthe Dekker Qiu Ying van de Pol Joelle van Bennekom Arjan Schoneveld Marjet J M Klein Avink Robbert J de Winter Gerard Pasterkamp Gert J de Borst Dominique P V de Kleijn Source Type: research